from twisted.python import components
from zope.interface import Interface, implements
class Service(object):
    pass
class IService(Interface):
    pass
class ServiceAdapter(object):
    implements(IService)
    def __init__(self, service):
        self.service = service
components.registerAdapter(ServiceAdapter, Service, IService)
s = Service()
sa = IService(s)
sb = IService(s)
print sa, sb

# ...
@zope.component.adapter(Service)
@zope.interface.implementer(IService)
def myadapter(svc):
    if not svc in myglobaldict:
        myglobaldict[svc] = ServiceAdapter(svc)
    return myglobaldict[svc]
#twisted.python.components.registerAdapter(myadapter, Service)
# или
#zope.component.provideAdapter(myadapter)
# а лучше
zope.component.getSiteManager()\
    .registerAdapter(myadapter)
# ...

# ...
class ServiceAdapterProvider(object):
    def __init__(self):
        self.mydict = {}
        twisted.python.components.registerAdapter(self.adapter, Service, IService)
    def adapter(self, svc):
        if not svc in self.mydict:
            self.mydict[svc] = ServiceAdapter(svc)
        return self.mydict[svc]
# ...