>>> import re
>>> str='<a href="1.ru">11111</a>, <a href="2.ru">222222</a>'
>>> re.findall(r'<a.*>.*</a>', str)
['<a href="1.ru">11111</a>, <a href="2.ru">222222</a>']
>>>

re.findall(r'<a[^>]*>[^<]*</a>', str)

re.findall(r'<a.*?>.*?</a>', str)

re.findall(r'<a[^>]*>[^<]*</a>', str)

>>> import lxml.html
>>> 
>>> s = """<a href="1.ru">11111</a>, <a href="2.ru">222222</a>"""
>>> 
>>> html = lxml.html.fromstring(s)
>>> data = [(node.attrib['href'], node.text)
...         for node in html.iterchildren('a')]
>>> print(data)
[('1.ru', '11111'), ('2.ru', '222222')]
>>>