#!/usr/bin/env python 
import tkinter as tk
class Application(tk.Frame): 
    def __init__(self, master=None):
        tk.Frame.__init__(self, master) 
        self.grid() 
        self.createWidgets()
    def createWidgets(self):
        self.label1 = tk.Label(self, text = "расрас")
        self.label1.pack()
        self.quitButton = tk.Button(self, text='Quit',
        command = self.remApp) 
        self.quitButton.pack(side = BOTTOM)
    def remApp(self):
        self.destroy()
app = Application() 
app.master.title('Sample application') 
app.mainloop()

app.master.title('Sample application') 

self.master.destroy()

side = BOTTOM

side="bottom"