qwe = ['alex','billy','charlie']
asd = ['alpha','beta','gamma']
zxc = dict.fromkeys(qwe,dict.fromkeys(asd))
for i in qwe:
    for j in asd:
        zxc[i].update({j: (qwe.index(i)+1)*10 + asd.index(j)})
print(zxc)

  
qwe = ['alex','billy','charlie']
asd = ['alpha','beta','gamma']
out ={name: {k: i*10 + j for j, k in enumerate(asd)} for i, name in enumerate(qwe, 1)}
print(out)

  
for i, name in enumerate(qwe, 1):
    out[name] = {}
    for j, k in enumerate(asd):
        out[name].update({k: i * 10 + j})