ibm_db Python DBI driver for DB2 (LUW, zOS, i5) and IDS This extension is the implementation of Python Database API Specification v2.0 The extension supports DB2 (LUW, zOS, i5) and IDS (Informix Dynamic Server)
http://code.google.com/p/ibm-db/
http://pypi.python.org/pypi/ibm_db
http://antoniocangiano.com/rubypython-and-db2-drivers/